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Finally, given the minimal de novo generation of OLGs from OPCs in the brains of adult humans, including MS patients (Yeung et al., 2014, 2019), efforts should also be made to identify factors capable of boosting mature OLG survival and plasticity during acute demyelination

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Unlike many regenerative peptides that originate from endocrine or immune signalling, BPC-157 emerged from gastrointestinal research before becoming widely investigated across musculoskeletal, vascular and connective tissue biology